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Tylenol 8 HR Arthritis Pain Extended Release Caplets, 650 Mg (290 ct.)

Health & Medicines

Why We Love This

These caplets have a bi-layer design to deliver fast-acting arthritis pain relief for up to eight hours.

About this item

  • Temporarily relieves minor arthritis pain
  • 650 milligrams of acetaminophen per caplet
  • Fast-acting relief lasts up to 8 hours
  • Bi-layer caplet design
  • Acetaminophen extended release


TYLENOL® 8 HR Arthritis Pain Extended Release Caplets, 650 Mg (290 ct.) are made by TYLENOL, the #1 doctor-recommended brand of pain relievers.

What Are the Recommended Uses of TYLENOL 8 HR Arthritis Pain Extended Release Caplets?

These TYLENOL 8-hour 650mg caplets temporarily relieve the minor pain of arthritis. Count on the 650 milligrams of acetaminophen in TYLENOL Extended Release Caplets for the temporary relief of aches and pains that are associated with backache, muscular aches, the common cold, headaches, toothaches, and premenstrual and menstrual cramps. These caplets also temporarily reduce fever.

What Does Extended Release Mean?

The bi-layer design of TYLENOL 8 HR Arthritis Pain Extended Release Caplets delivers fast-acting relief that lasts up to eight hours. Bi-layer design, specifically, means that each caplet has two layers of pain relief. The first dissolves quickly, and the second lasts all day, providing pain relief for up to eight hours in these acetaminophen extended release caplets.

Dosage Information

Follow the dosage instructions to make sure you're taking these TYLENOL 650 mg caplets properly.

Adults should take two caplets every eight hours with water. Swallow the caplets whole; do not crush, chew, split, or dissolve them. Do not take more than six caplets in 24 hours. Do not use these acetaminophen 650 mg caplets for more than 10 days unless directed by a doctor

For those under age 18: ask a doctor for dosage recommendations.

History of TYLENOL Brand

Before there was such a product as TYLENOL 8-hour arthritis pain caplets, Robert McNeil opened McNeil Pharmacy in Philadelphia, back in 1879. McNeil manufactured and sold medicines to the city's many hospitals and doctors. His son, Robert Lincoln McNeil, joined the business in 1904 and focused on expanding their phamaceutical offerings. In 1955, McNeil introduced TYLENOL Elixir for Children, the first aspirin-free pain reliever, available only by prescription. In the years since, TYLENOL has become one of the most recognized and respected brands, with new variations constantly in development, such as TYLENOL Arthritis Extended Release Caplets.


We can ship to virtually any address in the world. Note that there are restrictions on some products, and some products cannot be shipped to international destinations.

When you place an order, we will estimate shipping and delivery dates for you based on the availability of your items and the shipping options you choose. We Offer a very competitive shipping rates to Canada, Europe, and the rest of the World!

Our goal is to offer you the best shipping options, no matter where you live. Every day, we deliver to hundreds of customers across the world, ensuring that we provide the very highest levels of responsiveness to you at all times.

Returns Policy

If you are not completely satisfied with your order, We offer a 30-days 100% money-back guarantee with no-question-asked. If 30 days have gone by since your delivery, unfortunately, we can’t offer you a refund or exchange. To be eligible for a return, your item must be unused and in the same condition that you received it. It must also be in the original packaging.

You may return most new, unopened items within 30 days of delivery for a full refund. We'll also pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.).

If you need to return an item, simply login to your account, view the order using the 'Complete Orders' link under the My Account menu and click the Return Item(s) button. We'll notify you via e-mail of your refund once we've received and processed the returned item.

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